Human LTBR Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human LTBR Protein, hFc Tag

Human LTBR Protein, hFc Tag

产品编号

KMP2656

别名

淋巴毒素β受体, Human LTBR Protein, hFc Tag, LTBR

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	淋巴毒素β受体, Human LTBR Protein, hFc Tag, LTBR
Catalog Number	KMP2656
Product Description	The Human LTBR Protein(KMP2656) is produced in HEK293 Cells. The target gene encoding the human LTBR (NP_002333.1) (Gln31-Met227) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	LTBR
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	LTBR (lymphotoxin beta receptor (TNFR superfamily, member 3)) is a member of the tumor necrosis factor (TNF) family of receptors. The tumor necrosis factor receptor is a trimeric cytokine receptor that binds tumor necrosis factors. The receptor cooperates with an adaptor protein (such as TRADD, TRAF, RIP), which is important in determining the outcome of the response. LTBR is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. LTBR specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphotoxin-beta). LTBR and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of this protein can trigger apoptosis. Not only does the LTBR help trigger apoptosis, but it can also lead to the release of the cytokine interleukin 8. Overexpression of LTBR in HEK293 cells increases IL-8 promoter activity and leads to IL-8 release. It is also essential for the development and organization of the secondary lymphoid organs and chemokine release.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	47.8 kDa

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