Human NKG2D Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human NKG2D Protein, hFc Tag

Human NKG2D Protein, hFc Tag

产品编号

KMP2653

别名

杀伤细胞凝集素样受体 K 亚家族成员 1, Human NKG2D Protein, hFc Tag, NKG2D

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	杀伤细胞凝集素样受体 K 亚家族成员 1, Human NKG2D Protein, hFc Tag, NKG2D
Catalog Number	KMP2653
Product Description	The Human NKG2D Protein(KMP2653) is produced in CHO Cells. The target gene encoding the human NKG2D (NP_031386.2) (Phe78-Val216) is expressed with the Fc region of human IgG1 at the N-terminus.
Molecular Name	NKG2D
Species	Human
Host	CHO Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular proteins incapable to transduce signals. To transduce signals, NKG2D needs adaptor proteins and it uses two adaptor proteins, DAP10 and DAP12. These two adaptor proteins associate as homodimers to NKG2D- therefore the entire receptor complex appears as a hexamer. NKG2D can send co-stimulatory signals to activate CD8 T cells. NKG2D also plays an important role in viral control. Cellular stress can induce ligands for NKG2D which results in the cell susceptible to NK cell-mediated lysis.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	46.5 kDa

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