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Human PDGFRB Protein, hFc Tag

Human PDGFRB Protein, hFc Tag

产品编号

KMP2638

别名

血小板衍生生长因子受体β, Human PDGFRB Protein, hFc Tag, PDGFRB

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias血小板衍生生长因子受体β, Human PDGFRB Protein, hFc Tag, PDGFRB
Catalog NumberKMP2638
Product DescriptionThe Human PDGFRB Protein(KMP2638) is produced in HEK293 Cells. The target gene encoding the human PDGFRB (NP_002600.1) (Met1-Phe530) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular NamePDGFRB
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behAvior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD140b, also known as PDGFRB, is a member of the CD system. CD140b is a cell surface tyrosine kinase receptor essencial for development interacting with the platelet-derived growth factors (PDGFs) which serves as mitogens for mesenchymal cells. CD140b can bind with platelet-derived growth factor (PDGF)-B, that are secreted by tumors and phosphorylation of PDGFR-β was correlated with depth of cancer invasion at statistically significant level.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight82.8 kDa

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