Human PDGFRB Protein, hFc Tag
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产品编号
KMP2638
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别名
血小板衍生生长因子受体β, Human PDGFRB Protein, hFc Tag, PDGFRB
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规格
- 50ug
- 100ug
- 200ug
Alias | 血小板衍生生长因子受体β, Human PDGFRB Protein, hFc Tag, PDGFRB |
Catalog Number | KMP2638 |
Product Description | The Human PDGFRB Protein(KMP2638) is produced in HEK293 Cells. The target gene encoding the human PDGFRB (NP_002600.1) (Met1-Phe530) is expressed with the Fc region of human IgG1 at the C-terminus. |
Molecular Name | PDGFRB |
Species | Human |
Host | HEK293 Cells |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH7.4 |
Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behAvior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD140b, also known as PDGFRB, is a member of the CD system. CD140b is a cell surface tyrosine kinase receptor essencial for development interacting with the platelet-derived growth factors (PDGFs) which serves as mitogens for mesenchymal cells. CD140b can bind with platelet-derived growth factor (PDGF)-B, that are secreted by tumors and phosphorylation of PDGFR-β was correlated with depth of cancer invasion at statistically significant level. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 82.8 kDa |