Human CCL18 Protein, His Tag_天津卡梅德科技发展有限公司

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Human CCL18 Protein, His Tag

Human CCL18 Protein, His Tag

产品编号

KMP2637

别名

趋化因子CC配体18, Human CCL18 Protein, His Tag, CCL18

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	趋化因子CC配体18, Human CCL18 Protein, His Tag, CCL18
Catalog Number	KMP2637
Product Description	The Human CCL18 Protein(KMP2637) is produced in Yeast. The target gene encoding human CCL18 (NP_002979.1) (Ala21-Ala89) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	CCL18
Species	Human
Host	Yeast
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) and promotes malignant behAviors of various human cancer types. CCL18 has a correlation with cardiac function in patients with AAMI and it might be considered as an indicator of poor LVEF in patients with AAMI. Circulating and WAT-secreted CCL18 correlates with insulin resistance and metabolic risk score. Because CCL18 is macrophage-specific and associates with adipose immune gene expression, it may constitute a marker of WAT inflammation. Macrophages are thought to be the main source of CCL18, and the effect of pirfenidone, an anti-fibrotic agent for idiopathic pulmonary fibrosis, on the expression of CCL18 in macrophages warrants investigation.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	9.2 kDa

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