Human CCL14 Protein, His Tag
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产品编号
KMP2626
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别名
CXC 趋化因子配体 14, Human CCL14 Protein, His Tag, CCL14
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规格
- 50ug
- 100ug
- 200ug
Alias | CXC 趋化因子配体 14, Human CCL14 Protein, His Tag, CCL14 |
Catalog Number | KMP2626 |
Product Description | The Human CCL14 Protein(KMP2626) is produced in E. coli. The target gene encoding the amino acids (Gly 28-Asn 93) of human CCL14 (Q16627-1) is expressed, with a polyHistide tag at the N-terminus. |
Molecular Name | CCL14 |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, pH8.0 |
Background | CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is of recent interest because of its natural ability, upon proteolytic processing of the first eight NH2-terminal residues, to bind to and signal through the human immunodeficiency virus type-1 (HIV-1) co-receptor, CC chemokine receptor 5 (CCR5). Embryo implantation is a complex process involving blastocyst attachment to the endometrial epithelium and subsequent trophoblast invasion of the decidua. We have previously shown that the chemokines CX3CL1 and CCL14 are abundant in endometrial vasculature, epithelial, and decidual cells at this time, and that their receptors, CX3CR1 and CCR1, are present on invading human trophoblasts. CX3CL1 and CCL14 promote trophoblast migration. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 9.3 kDa |