Human CCL11 Protein, His Tag
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产品编号
KMP2623
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别名
嗜酸性粒细胞趋化蛋白, Human CCL11 Protein, His Tag, CCL11
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规格
- 50ug
- 100ug
- 200ug
Alias | 嗜酸性粒细胞趋化蛋白, Human CCL11 Protein, His Tag, CCL11 |
Catalog Number | KMP2623 |
Product Description | The Human CCL11 Protein(KMP2623) is produced in E. coli. The target gene encoding the human CCL11 (P51671) (Gly 24-Pro 97) is expressed, with a polyHistide tag at the N-terminus. |
Molecular Name | CCL11 |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug, 200ug |
Purity | >95% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | PBS, 10% Glycerol, pH7.5 |
Background | CCL11 or chemokine (C-C motif) ligand 11 is a member of the chemokine (C-C motif) ligand family. Chemokin (C-C motif) ligand 11 is a member of the chemokine family. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. They share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. CCL11 is implicated in allergic responses through selectively recruiting eosinophils by inducing their chemotaxis. The effects of CCL11 are mediated by its binding to chemokine receptor. Increased CCL11 levels in blood plasma are associated with aging in mice. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 10.8 kDa |