Human C-MPL Protein, His Tag_天津卡梅德科技发展有限公司

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Human C-MPL Protein, His Tag

Human C-MPL Protein, His Tag

产品编号

KMP2607

别名

血小板生成素受体, Human C-MPL Protein, His Tag, C-MPL

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	血小板生成素受体, Human C-MPL Protein, His Tag, C-MPL
Catalog Number	KMP2607
Product Description	The Human C-MPL Protein(KMP2607) is produced in HEK293 Cells. The target gene encoding the Human MPL (P40238-1) (Met1-Trp491) is expressed with a polyhistidine tag at the C-terminus.
Molecular Name	C-MPL
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number of cells of hematopoietic origin. C-MPL is homologous with members of the hematopoietic receptor superfamily. The presence of anti-sense oligodeoxynucleotides of C-Mpl inhibited megakaryocyte colony formation. Thrombopoietin is the ligand for C-Mpl. It was shown to be the major regulator of megakaryocytopoiesis and platelet formation. Defects in c-MPL are a cause of congenital amegakaryocytic thrombocytopenia which is a disease characterized by isolated thrombocytopenia and Megakaryocytopenia with no physical anomalies. Defects in c-MPL also cause thrombocythemia type 2 and myelofibrosis with myeloid metaplasia.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	54 kDa

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