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Human IL10RA Protein, His Tag

Human IL10RA Protein, His Tag

产品编号

KMP2601

别名

白介素 10 受体亚基 α, Human IL10RA Protein, His Tag, IL10RA

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias白介素 10 受体亚基 α, Human IL10RA Protein, His Tag, IL10RA
Catalog NumberKMP2601
Product DescriptionThe Human IL10RA Protein(KMP2601) is produced in HEK293 Cells. The target gene encoding the human IL10RA (NP_001549.2) (Met1-Asn235) is expressed with a polyhistidine tag at the C-terminus.
Molecular NameIL10RA
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundIL10RA (Interleukin 10 Receptor Subunit Alpha, also known as CD210) is a Protein Coding gene. The protein encoded by this gene is a receptor for interleukin 10. Two transcript variants, one protein-coding, and the other, not protein-coding have been found for this gene. CD210 belongs to the type II cytokine receptor family. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. Activation of CD210 leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. CD210 is broadly expressed in the spleen, bone marrow, and other tissues. Diseases associated with IL10RA include Inflammatory Bowel Disease 28, Autosomal Recessive, and Inflammatory Bowel Disease 28.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight25.8 kDa

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