Human IL13RA2 Protein, His Tag_天津卡梅德科技发展有限公司

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Human IL13RA2 Protein, His Tag

Human IL13RA2 Protein, His Tag

产品编号

KMP2569

别名

白细胞介素 13 受体亚基 α 2, Human IL13RA2 Protein, His Tag, IL13RA2

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	白细胞介素 13 受体亚基 α 2, Human IL13RA2 Protein, His Tag, IL13RA2
Catalog Number	KMP2569
Product Description	The Human IL13RA2 Protein(KMP2569) is produced in HEK293 Cells. The target gene encoding the extracellular domain of human IL13Rα2 (NP_000631.1) (Met1-Leu342) is expressed with the a polyhistidine tag at the C-terminus. The purified protein is biotinylated in vitro.
Molecular Name	IL13RA2
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>85% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Interleukin-13 receptor subunit alpha-2 (IL13RA2/IL-13RA2) is also known as cluster of differentiation 213A2 (CD213A2), IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, and IL-13RA2. The IL13RA2 is often overexpressed in brain tumors, making Il13ra2 one of the vaccine targets for immunotherapy of glioma. IL13RA2/IL-13RA2 is a cancer-associated receptor that is present in greater than 80% of High-Grade Astrocytomas (HGA) and has recently been recognized as a cytokine that predisposes breast cancer cells to metastasize. Expression of IL13Rα2 was rapidly lost from the surface of transduced cells grown in culture. The loss appeared to be related to ligands present in fetal bovine serum in the medium. None of the malignant glioma cell lines cultivated in vitro and tested to date exhibited the IL13Rα2 receptor. A recombinant virus (R5111) enters cells via its interaction with the IL13Rα2 receptor in a manner that cannot be differentiated from the interaction of wild-type virus with its receptors.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	38 kDa

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