Human CD40L Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human CD40L Protein, hFc Tag

Human CD40L Protein, hFc Tag

产品编号

KMP2530

别名

肿瘤坏死因子相关激活蛋白, Human CD40L Protein, hFc Tag, CD40L

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	肿瘤坏死因子相关激活蛋白, Human CD40L Protein, hFc Tag, CD40L
Catalog Number	KMP2530
Product Description	The Human CD40L Protein(KMP2530) is produced in HEK293 Cells. The target gene encoding the soluble form of human CD40L (NP_000065.1) (Met 113-Leu 261) is fused with the Fc region of human IgG1 at the N-terminus.
Molecular Name	CD40L
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>90% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behAvior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD154, also known as CD40 ligand or CD40L, is a member of the TNF superfamily. While CD154 was originally found on T cell surface, its expression has since been found on a wide variety of cells, including platelets, mast cells, macrophages and NK cells. CD154's ability is achieved through binding to the CD40 on antigen-presenting cells (APC). In the macrophage cells, the primary signal for activation is IFN-γ from Th1 type CD4 T cells. The secondary signal is CD40L on the T cell, which interacting with the CD40 molecules, helping increase the level of activation.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	42.8 kDa

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