Human TARC Protein, His Tag
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产品编号
KMP2528
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别名
胸腺激活调节趋化因子, Human TARC Protein, His Tag, TARC
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规格
- 50ug
- 100ug
- 200ug
Alias | 胸腺激活调节趋化因子, Human TARC Protein, His Tag, TARC |
Catalog Number | KMP2528 |
Product Description | The Human TARC Protein(KMP2528) is produced in Insect Cells. The target gene encoding the full length of human CCL17 (Q92583-1) (Met 1-Ser 94) is expressed, fused with a polyhistidine tag at the C-terminus. |
Molecular Name | TARC |
Species | Human |
Host | Insect Cells |
Size | 50ug, 100ug, 200ug |
Purity | >90% as determined by SDS-PAGE |
Purification | Affinity purification |
Endotoxin | <1.0 EU/ug determined by the LAL method |
Formulation | 20mM Tris, 500mM NaCl, 10% Glycerol, pH7.4 |
Background | Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4. |
Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
Molecular Weight | 9.5 kDa |