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Human TARC Protein, His Tag

Human TARC Protein, His Tag

产品编号

KMP2528

别名

胸腺激活调节趋化因子, Human TARC Protein, His Tag, TARC

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias胸腺激活调节趋化因子, Human TARC Protein, His Tag, TARC
Catalog NumberKMP2528
Product DescriptionThe Human TARC Protein(KMP2528) is produced in Insect Cells. The target gene encoding the full length of human CCL17 (Q92583-1) (Met 1-Ser 94) is expressed, fused with a polyhistidine tag at the C-terminus.
Molecular NameTARC
SpeciesHuman
HostInsect Cells
Size50ug, 100ug, 200ug
Purity>90% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation20mM Tris, 500mM NaCl, 10% Glycerol, pH7.4
BackgroundChemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 17 (CCL17), also known as thymus and activation regulated chemokine(TARC), is a small cytokine belonging to the C-C chemokine family. CCL17 is expressed maily in thymus and transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. CCL17 can induce chemotaxis in T cells by binding with the chemokine receptor CCR4.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight9.5 kDa

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