Human DKK1 Protein, hFc Tag_天津卡梅德科技发展有限公司

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Human DKK1 Protein, hFc Tag

Human DKK1 Protein, hFc Tag

产品编号

KMP2509

别名

Dickkopf相关蛋白-1, Human DKK1 Protein, hFc Tag, DKK1

规格

50ug
100ug
200ug

DATASHEET MSDS

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产品介绍

Alias	Dickkopf相关蛋白-1, Human DKK1 Protein, hFc Tag, DKK1
Catalog Number	KMP2509
Product Description	The Human DKK1 Protein(KMP2509) is produced in HEK293 Cells. The target gene encoding the human DKK1 (NP_036374.1) (Met2-His266) is expressed with the Fc region of human IgG1 at the C-terminus.
Molecular Name	DKK1
Species	Human
Host	HEK293 Cells
Size	50ug, 100ug, 200ug
Purity	>95% as determined by SDS-PAGE
Purification	Affinity purification
Endotoxin	<1.0 EU/ug determined by the LAL method
Formulation	PBS, pH7.4
Background	Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majority of lung cancers, esophageal squamous cell carcinomas, and hormone-resistant breast cancers, while DKK-1 expression is decreased in malignant melanoma and colorectal cancers.
Storage Condition	Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping Condition	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight	52.5 kDa

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