Human CD155 Protein
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产品编号
KMP2489
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别名
PVR 细胞粘附分子, Human CD155 Protein, CD155
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规格
- 50ug
- 100ug
- 200ug
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- Human CD155 Protein
产品介绍
| Alias | PVR 细胞粘附分子, Human CD155 Protein, CD155 |
| Catalog Number | KMP2489 |
| Product Description | The Human CD155 Protein(KMP2489) is produced in HEK293 Cells. The target gene encoding the human PVR (AAA36462.1) (Met1-Asn343) is expressed. |
| Molecular Name | CD155 |
| Species | Human |
| Host | HEK293 Cells |
| Size | 50ug, 100ug, 200ug |
| Purity | >90% as determined by SDS-PAGE |
| Purification | Affinity purification |
| Endotoxin | <1.0 EU/ug determined by the LAL method |
| Formulation | PBS, pH7.4 |
| Background | CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity. |
| Storage Condition | Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. |
| Shipping Condition | In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice. |
| Molecular Weight | 35.1 kDa |
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