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Human Vimentin Protein, His Tag

Human Vimentin Protein, His Tag

产品编号

KMP2455

别名

波形蛋白, Human Vimentin Protein, His Tag, Vimentin

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias波形蛋白, Human Vimentin Protein, His Tag, Vimentin
Catalog NumberKMP2455
Product DescriptionThe Human Vimentin Protein(KMP2455) is produced in Insect Cells. The target gene encoding the human VIM (Met1-Glu466) (P08670) is expressed with a C-terminal polyhistidine tag.
Molecular NameVimentin
SpeciesHuman
HostInsect Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
Formulation40% Acetonitrile, 0.1% TFA
BackgroundVimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. Therefore, in general, it is accepted that vimentin is the cytoskeletal component responsible for maintaining cell integrity. Vimentin is also responsible for stabilizing cytoskeletal interactions. It is found that vimentin control the transport of low-density lipoprotein. It has been used as a sarcoma tumor marker to identify mesenchyme.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight55.11 kDa

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