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Human Nectin-2 Protein, hFc Tag, Avi Tag

Human Nectin-2 Protein, hFc Tag, Avi Tag

产品编号

KMP2445

别名

粘连蛋白细胞粘附分子, Human Nectin-2 Protein, hFc Tag, Avi Tag, Nectin-2

规格
  • 50ug
  • 100ug
  • 200ug
产品介绍
Alias粘连蛋白细胞粘附分子, Human Nectin-2 Protein, hFc Tag, Avi Tag, Nectin-2
Catalog NumberKMP2445
Product DescriptionThe Human Nectin-2 Protein(KMP2445) is produced in HEK293 Cells. The target gene encoding the human NECTIN2 (NP_002847.1)(Met1-Leu360) is expressed with a c-terminal Avi tagged Fc region of human IgG1 at the C-terminus (Fc-Avi). The expressed protein is biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
Molecular NameNectin-2
SpeciesHuman
HostHEK293 Cells
Size50ug, 100ug, 200ug
Purity>95% as determined by SDS-PAGE
PurificationAffinity purification
Endotoxin<1.0 EU/ug determined by the LAL method
FormulationPBS, pH7.4
BackgroundCluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+ T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy.
Storage ConditionAliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Shipping ConditionIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. If supplied as liquid, the proteins will be shipped with dry ice.
Molecular Weight64.08 kDa

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