Recombinant Human STUB1/CHIP Protein, No Tag
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产品编号
KMH1760
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别名
CHIP, SCA48, UBOX1, SCAR16, HSPABP2, NY CO 7, SDCCAG7, STIP1 homology and U box containing protein 1
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规格
- 50ug
- 100ug
Alias | CHIP, SCA48, UBOX1, SCAR16, HSPABP2, NY CO 7, SDCCAG7, STIP1 homology and U box containing protein 1 |
Catalog Number | KMH1760 |
Molecular Name | STUB1 |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | Please contact our customer service for more information. |
Formulation | PBS |
Background | CHIP, also known as STUB1, is a cytoplasmic protein whose amino acid sequence is highly conserved across species. CHIP interacts with the molecular chaperones Hsc7-Hsp7 and Hsp9 through its TPR domain, whereas its U-box domain contains its E3 ubiquitin ligase activity. Its interaction with these molecular chaperones results in client substrate ubiquitylation and degradation by the proteasome. Thus, CHIP acts to tilt the folding-refolding machinery toward the degradative pathway, and it serves as a link between the two. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 27.28 kDa |
Note | 仅供科研使用 |