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Recombinant Human STUB1/CHIP Protein, No Tag

Recombinant Human STUB1/CHIP Protein, No Tag

产品编号

KMH1760

别名

CHIP, SCA48, UBOX1, SCAR16, HSPABP2, NY CO 7, SDCCAG7, STIP1 homology and U box containing protein 1

规格
  • 50ug
  • 100ug
产品介绍
AliasCHIP, SCA48, UBOX1, SCAR16, HSPABP2, NY CO 7, SDCCAG7, STIP1 homology and U box containing protein 1
Catalog NumberKMH1760
Molecular NameSTUB1
SpeciesHuman
HostE. coli
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
EndotoxinPlease contact our customer service for more information.
FormulationPBS
BackgroundCHIP, also known as STUB1, is a cytoplasmic protein whose amino acid sequence is highly conserved across species. CHIP interacts with the molecular chaperones Hsc7-Hsp7 and Hsp9 through its TPR domain, whereas its U-box domain contains its E3 ubiquitin ligase activity. Its interaction with these molecular chaperones results in client substrate ubiquitylation and degradation by the proteasome. Thus, CHIP acts to tilt the folding-refolding machinery toward the degradative pathway, and it serves as a link between the two.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight27.28 kDa
Note仅供科研使用

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