Recombinant Human SPINK1 Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human SPINK1 Protein, His Tag

Recombinant Human SPINK1 Protein, His Tag

产品编号

KMH1744

别名

TCP, PCTT, PSTI, TATI, Spink3, serine peptidase inhibitor Kazal type 1

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	TCP, PCTT, PSTI, TATI, Spink3, serine peptidase inhibitor Kazal type 1
Catalog Number	KMH1744
Molecular Name	SPINK1
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Serine Protease Inhibitor KazalType 1 (SPINK1) is a trypsin inhibitor that prevent the trypsincatalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP). Recombinant SPINK1 protein (rSPINK1) stimulated cell proliferation in benign RWPE as well as cancerous prostate cells. The research result indicated that the potential of SPINK1 as an extracellular therapeutic target in prostate cancer. In contrast, knockdown of SPINK1 in 22RV1 cells inhibited cell proliferation, cell invasion, and tumor growth in xenograft assays.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	6.16 kDa
Note	仅供科研使用

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