Recombinant Human SPARC Protein, His Tag
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产品编号
KMH1741
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别名
ON, ONT, OI17, BM 40, secreted protein acidic and cysteine rich
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规格
- 50ug
- 100ug
产品中心
Alias | ON, ONT, OI17, BM 40, secreted protein acidic and cysteine rich |
Catalog Number | KMH1741 |
Molecular Name | SPARC |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | SPARC, an acronym for secreted protein, acidic and rich in cysteine, is also known as osteonectin or BM-4. It is the founding member of a family of secreted matricellular proteins with similar domain structure. The 33 amino acid, 43 kDa protein contains a 17 aa signal sequence, an N-terminal acidic region that binds calcium, a follistatin domain containing Kazal-like sequences, and a C-terminal extracellular calcium (EC) binding domain with two EF-hand motifs. SPARC is produced by fibroblasts, capillary endothelial cells, platelets and macrophages, especially in areas of tissue morphogenesis and remodeling. SPARC shows context-specific effects, but generally inhibits adhesion, spreading and proliferation, and promotes collagen matrix formation. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 31.46 kDa |
Note | 仅供科研使用 |
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