Recombinant Mouse Serpind1 Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Mouse Serpind1 Protein, His Tag

Recombinant Mouse Serpind1 Protein, His Tag

产品编号

MOP2268

别名

HCII, Hcf2, HC II, AA985900, AI303446, serine(or cysteine) peptidase inhibitor, clade D, member 1

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	HCII, Hcf2, HC II, AA985900, AI303446, serine(or cysteine) peptidase inhibitor, clade D, member 1
Catalog Number	MOP2268
Molecular Name	Serpind1
Species	Mouse
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	SerpinD1, also known as heparin cofactor II (HCⅡ), is a member of Serpin superfamily of the serine proteinase inhibitors. HCII is a glycoprotein in human plasma that inhibits thrombin and chymotrypsin, and the rate of inhibition of thrombin is rapidly increased by Dermatan sulfate (DS), heparin (H) and glycosaminoglycans(GAG). The stimulatory effect of glycosaminoglycans on the inhibition is mediated, in part, by the N-terminal acidic domain of HCII. Interestingly, a C-terminal His-tagged recombinant HCII exhibits enhanced activity of thrombin inhibition. It has been suggested that HCII plays an unique and important role in vascular homeostasis, and accordingly mutations in this gene or congenital HCII deficiency is potentially associated with thrombosis.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	50.05 kDa
Note	仅供科研使用

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