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Recombinant Human Semaphorin 4A/SEMA4A Protein, His Tag

Recombinant Human Semaphorin 4A/SEMA4A Protein, His Tag

产品编号

KMH1677

别名

RP35, SEMB, SEMAB, CORD10, semaphorin 4A

规格
  • 50ug
  • 100ug
产品介绍
AliasRP35, SEMB, SEMAB, CORD10, semaphorin 4A
Catalog NumberKMH1677
Molecular NameSEMA4A
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundSemaphorin-4A (SEMA4A) belongs to the semaphorin family which contains a Ig-like C2-type domain, a PSI domain and a Sema domain. SEMA4A is expressed from day 1 in the embryo, and low levels are found between days 1-12. SEMA4A is a cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. It plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. SEMA4A promotes phosphorylation of TIMD2, inhibits angiogenesis, and promotes axon growth cone collapse, Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight71.5 kDa
Note仅供科研使用

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