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Recombinant Human pro-Kallikrein 5/KLK5 Protein, His Tag

Recombinant Human pro-Kallikrein 5/KLK5 Protein, His Tag

产品编号

KMH1602

别名

SCTE, KLKL2, KLK L2, kallikrein related peptidase 5

规格
  • 50ug
  • 100ug
产品介绍
AliasSCTE, KLKL2, KLK L2, kallikrein related peptidase 5
Catalog NumberKMH1602
Molecular NameKLK5
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundHuman tissue Kallikrein 5 (hK5, also known as stratum corneum tryptic enzyme) is a serine protease of the human tissue Kallikrein gene family. The deduced amino acid sequence of human KLK5 consists of a signal peptide (Met1 to Gly22), a pro region (Val23 to Arg66) and a mature/active enzyme (Ile67 to Ser293). KLK5 is expressed mainly in skin, breast, brain and testis and to a lesser extent in many other tissues. KLK5 overexpression is an indicator of poor prognosis in ovarian cancer. hK5 is a candidate physiological activator of hK7 in the stratum corneum. Indeed, rhK5 can be used to activate rhK7 by incubating rhK5 with recombinant human (rh) K7 (both at. 1 mg/mL) in 25 mM MES, 15 M NaCl, pH 5.5, at 37 centigrade overnight.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight29.81 kDa
Note仅供科研使用

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