Recombinant Human pro-Kallikrein 5/KLK5 Protein, His Tag
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产品编号
KMH1602
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别名
SCTE, KLKL2, KLK L2, kallikrein related peptidase 5
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规格
- 50ug
- 100ug
Alias | SCTE, KLKL2, KLK L2, kallikrein related peptidase 5 |
Catalog Number | KMH1602 |
Molecular Name | KLK5 |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | Human tissue Kallikrein 5 (hK5, also known as stratum corneum tryptic enzyme) is a serine protease of the human tissue Kallikrein gene family. The deduced amino acid sequence of human KLK5 consists of a signal peptide (Met1 to Gly22), a pro region (Val23 to Arg66) and a mature/active enzyme (Ile67 to Ser293). KLK5 is expressed mainly in skin, breast, brain and testis and to a lesser extent in many other tissues. KLK5 overexpression is an indicator of poor prognosis in ovarian cancer. hK5 is a candidate physiological activator of hK7 in the stratum corneum. Indeed, rhK5 can be used to activate rhK7 by incubating rhK5 with recombinant human (rh) K7 (both at. 1 mg/mL) in 25 mM MES, 15 M NaCl, pH 5.5, at 37 centigrade overnight. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 29.81 kDa |
Note | 仅供科研使用 |