Recombinant Human NgR3/RTN4RL1 Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human NgR3/RTN4RL1 Protein, His Tag

Recombinant Human NgR3/RTN4RL1 Protein, His Tag

产品编号

KMH1453

别名

NgR3, NGRH2, reticulon 4 receptor like 1

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	NgR3, NGRH2, reticulon 4 receptor like 1
Catalog Number	KMH1453
Molecular Name	RTN4RL1
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family. NgR is GPI-anchored and contains eight leucine-rich repeats (LRR), it is the neuronal receptor for the myelin- associated proteins Nogo-A, OMgp (oligodendrocyte myelin glycoprotein), and MAG (myelin-associated glycoprotein) and mediates the inhibition of CNS axonal regeneration both in vitro and in vivo. NgR2 and NgR3 have similar structure and distinct but overlapping expression versus NgR. NgR2 can be metalloproteinase-cleaved to release a soluble ectodomain. NgR2 has also been shown to bind MAG, but ligands for NgR3 have not yet been determined. Mature huaman NgR3 shares 88%, 88%, 48% and 44% amino acid identity with mature mouse NgR3, rat NgR3, human NgRH1 and NgR, repectively.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	43.45 kDa
Note	仅供科研使用

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