首页
>>
产品中心
>>
蛋白产品
>>
重组蛋白
>
Recombinant Mouse Mmp12 Protein, His Tag

Recombinant Mouse Mmp12 Protein, His Tag

产品编号

MOP2227

别名

MME, Mmel, AV378681, matrix metallopeptidase 12

规格
  • 50ug
  • 100ug
产品介绍
AliasMME, Mmel, AV378681, matrix metallopeptidase 12
Catalog NumberMOP2227
Molecular NameMmp12
SpeciesMouse
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundMacrophage metalloelastase is an enzyme that in humans is encoded by the MMP12 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP"s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight48.95 kDa
Note仅供科研使用

登录

还没有账号?立即注册

注册

已有账号?立即登录

立即询价