Recombinant Human MICA Protein, His Tag
-
产品编号
KMH1402
-
别名
MIC A, PERB11.1, MICA MHC class I polypeptide related sequence A
-
规格
- 50ug
- 100ug
Alias | MIC A, PERB11.1, MICA MHC class I polypeptide related sequence A |
Catalog Number | KMH1402 |
Molecular Name | MICA |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | MIC-A (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig-like domains, but they have no capacity to bind peptide or interact with microglobulin. The genes encoding these proteins are found within the Major Histocompatibility Complex on human chromosome 6. The MICA locus is highly polymorphic with more than 5 recognized human alleles. MICA is absent from most cells but is frequently expressed in epithelial tumors and can be induced by bacterial and viral infections. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 26.95 kDa |
Note | 仅供科研使用 |