Recombinant Human MERTK Protein, His Tag
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产品编号
KMH1392
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别名
MER, RP38, c Eyk, c mer, Tyro12, MER proto oncogene, tyrosine kinase
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规格
- 50ug
- 100ug
Alias | MER, RP38, c Eyk, c mer, Tyro12, MER proto oncogene, tyrosine kinase |
Catalog Number | KMH1392 |
Molecular Name | MERTK |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | c-MER is a tyrosine kinase and a member of the MER/AXL/TYRO3 receptor kinase family. The c-MER gene encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. Functional knockout of c-MER in mice shows the mice to have macrophages deficient in the clearance of apoptotic thymocytes thereby demonstrating the critical role for c-MER in the engulfment and efficient clearance of apoptotic cells. Defects in c-MER have been associated with retinitis pigmentosa, a phenotype that can be reversed by replacement of the c-MER gene product. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 35.53 kDa |
Note | 仅供科研使用 |