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Recombinant Human MERTK Protein, His Tag

Recombinant Human MERTK Protein, His Tag

产品编号

KMH1392

别名

MER, RP38, c Eyk, c mer, Tyro12, MER proto oncogene, tyrosine kinase

规格
  • 50ug
  • 100ug
产品介绍
AliasMER, RP38, c Eyk, c mer, Tyro12, MER proto oncogene, tyrosine kinase
Catalog NumberKMH1392
Molecular NameMERTK
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
Backgroundc-MER is a tyrosine kinase and a member of the MER/AXL/TYRO3 receptor kinase family. The c-MER gene encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. Functional knockout of c-MER in mice shows the mice to have macrophages deficient in the clearance of apoptotic thymocytes thereby demonstrating the critical role for c-MER in the engulfment and efficient clearance of apoptotic cells. Defects in c-MER have been associated with retinitis pigmentosa, a phenotype that can be reversed by replacement of the c-MER gene product.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight35.53 kDa
Note仅供科研使用

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