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Recombinant Human M-CSF R/CSF1R/CD115 Protein, Fc Tag

Recombinant Human M-CSF R/CSF1R/CD115 Protein, Fc Tag

产品编号

KMH1384

别名

FMS, CSFR, FIM2, HDLS, C FMS, CD115, CSF 1R, BANDDOS, M CSF R, colony stimulating factor 1 receptor

规格
  • 50ug
  • 100ug
产品介绍
AliasFMS, CSFR, FIM2, HDLS, C FMS, CD115, CSF 1R, BANDDOS, M CSF R, colony stimulating factor 1 receptor
Catalog NumberKMH1384
Molecular NameCSF1R
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundMacrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight79.78 kDa
Note仅供科研使用

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