Recombinant Human MAN1B1 Protein, His Tag
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产品编号
KMH1373
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别名
MRT15, ERMAN1, ERManI, MANA ER, mannosidase alpha class 1B member 1
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规格
- 50ug
- 100ug
Alias | MRT15, ERMAN1, ERManI, MANA ER, mannosidase alpha class 1B member 1 |
Catalog Number | KMH1373 |
Molecular Name | MAN1B1 |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | Endoplasmic Reticulum Mannosyl-Oligosaccharide 1, 2-α-Mannosidase (MAN1B1) belongs to the glycosyl hydrolase 47 family. MAB1B1 is a single-pass type II membrane protein and widely expressed in many tissues. MAB1B1 is involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. MAB1B1 can be inhibited by both 1-deoxymannojirimycin (dMNJ) and kifunensine. Defects in MAN1B1 are the cause of mental retardation autosomal recessive type 15 (MRT15). Mental retardation is characterized by significantly below average general intellectual functioning, it is also associated with impairments in adaptative behavior and manifested during the developmental period. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 65.34 kDa |
Note | 仅供科研使用 |