Recombinant Human Legumain/LGMN Protein, His Tag
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产品编号
KMH1336
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别名
AEP, LGMN1, PRSC1, legumain
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规格
- 50ug
- 100ug
产品中心
Alias | AEP, LGMN1, PRSC1, legumain |
Catalog Number | KMH1336 |
Molecular Name | LGMN |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | Legumain, also known as LGMN, is a cysteine protease belonging to peptidase family C13 with a strict specificity for hydrolysis of asparaginyl bonds. Known previously only from plants and invertebrates, Legumain is discovered as a lysosomal endopeptidase in mammals. Mammalian legumain is a cysteine endopeptidase, inhibited by iodoacetamide and maleimides, but unaffected by compound E64. The mammalian legumain is involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Legumain activation is triggered by acidic pH and appears to be autocatalytic. Mouse LGMN is ubiquitously expressed and particularly abundant in kidney and placenta. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 45.76 kDa |
Note | 仅供科研使用 |
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