首页
>>
产品中心
>>
蛋白产品
>>
重组蛋白
>
Recombinant Mouse Kallikrein 7/Klk7 Protein, His Tag

Recombinant Mouse Kallikrein 7/Klk7 Protein, His Tag

产品编号

MOP2213

别名

SCCE, Prss6, kallikrein related peptidase 7(chymotryptic, stratum corneum)

规格
  • 50ug
  • 100ug
产品介绍
AliasSCCE, Prss6, kallikrein related peptidase 7(chymotryptic, stratum corneum)
Catalog NumberMOP2213
Molecular NameKlk7
SpeciesMouse
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundKallikrein-7 (KLK7) is also known as kallikrein-related peptidase 7, Stratum corneum chymotryptic enzyme, Serine protease 6, KLK7, and PRSS6, is a secreted protein which belongs to the peptidase S1 family and Kallikrein subfamily. KLK7 is secreted as an inactive zymogen in the stratum granulosum layer of the epidermis, requiring proteolytic cleavage of the short N-terminal pro-region to liberate activated enzyme. This may be performed by KLK5 or matriptase, which are in vitro activators of KLK7. Once active, KLK7 is able to cleave desmocollin and corneodesmosin. KLK7 activity is regulated by a number of endogenous protein inhibitors including LEKTI, SPINK6, elafin and alpha-2-Macroglobulin-like 1. Both Zn2+ and Cu2+ ions are also able to inhibit KLK7. Dysregulation of KLK7 has been linked to several skin disorders, and overexpression of KLK7 may provide a route for metastasis in several cancers.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight25.08 kDa
Note仅供科研使用

登录

还没有账号?立即注册

注册

已有账号?立即登录

立即询价