Recombinant Human ITM2B Protein, His Tag
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产品编号
KMH1285
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别名
BRI, FBD, ABRI, BRI2, E25B, E3 16, RDGCA, imBRI2, BRICD2B, integral membrane protein 2B
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规格
- 50ug
- 100ug
| Alias | BRI, FBD, ABRI, BRI2, E25B, E3 16, RDGCA, imBRI2, BRICD2B, integral membrane protein 2B |
| Catalog Number | KMH1285 |
| Molecular Name | ITM2B |
| Species | Human |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | Other protein |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervous system. CAA-ITM2B2 characterized by amyloid deposition in the walls of the blood vessels of the cerebrum, choroid plexus, cerebellum, spinal cord and retina. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 21.01 kDa |
| Note | 仅供科研使用 |
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