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Recombinant Human ITM2B Protein, His Tag

Recombinant Human ITM2B Protein, His Tag

产品编号

KMH1285

别名

BRI, FBD, ABRI, BRI2, E25B, E3 16, RDGCA, imBRI2, BRICD2B, integral membrane protein 2B

规格
  • 50ug
  • 100ug
产品介绍
AliasBRI, FBD, ABRI, BRI2, E25B, E3 16, RDGCA, imBRI2, BRICD2B, integral membrane protein 2B
Catalog NumberKMH1285
Molecular NameITM2B
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundIntegral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervous system. CAA-ITM2B2 characterized by amyloid deposition in the walls of the blood vessels of the cerebrum, choroid plexus, cerebellum, spinal cord and retina.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight21.01 kDa
Note仅供科研使用

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