Recombinant Mouse Il12rb2 Protein, Fc Tag
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产品编号
MOP2197
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别名
Ifnm, IL 12RB2, A930027I18Rik, interleukin 12 receptor, beta 2
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规格
- 50ug
- 100ug
Alias | Ifnm, IL 12RB2, A930027I18Rik, interleukin 12 receptor, beta 2 |
Catalog Number | MOP2197 |
Molecular Name | Il12rb2 |
Species | Mouse |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohns disease and leprosy, which is thought to contribute to the inflammatory response and host defense. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 95.07 kDa |
Note | 仅供科研使用 |