Recombinant Human IDO/IDO1 Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human IDO/IDO1 Protein, His Tag

Recombinant Human IDO/IDO1 Protein, His Tag

产品编号

KMH1244

别名

IDO, INDO, IDO 1, indoleamine 2, 3 dioxygenase 1

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	IDO, INDO, IDO 1, indoleamine 2, 3 dioxygenase 1
Catalog Number	KMH1244
Molecular Name	IDO1
Species	Human
Host	E. coli
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	Please contact our customer service for more information.
Formulation	PBS
Background	Indoleamine 2, 3-dioxygenase(IDO) is a hemecontaining intracellular dioxygenase catalyzing the degradation of the essential amino acid L-tryptophan toN-formylkynurenine. This degradation is the first and ratelimiting step of the L-kynurenine pathway. IDO is widely expressed in dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumor cells. In immune cells, its expression is mainly induced by cytokines such as IFN-γ, IFN-α, IFN-β, and IL-1. IDO has an antimicrobial function due to its decreasing the availability of the essential amino acid tryptophan in inflammatory environments.Recent studies have demonstrated that IDO induces immunosuppression during infection, pregnancy, transplantation, autoimmunity, and neoplasia.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	44.33 kDa
Note	仅供科研使用

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