Recombinant Human GFRA2 Protein, His Tag
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产品编号
KMH1162
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别名
NTNRA, RETL2, TRNR2, GDNFRB, NRTNR ALPHA, GDNF family receptor alpha 2
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规格
- 50ug
- 100ug
Alias | NTNRA, RETL2, TRNR2, GDNFRB, NRTNR ALPHA, GDNF family receptor alpha 2 |
Catalog Number | KMH1162 |
Molecular Name | GFRA2 |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | Glial cell line-derived neurotrophic factor family receptor alpha-2, also known as GFRA2, is the cognate co-receptor for the neurotrophic factor neurturin that is selectively expressed by isolectin B(4) (IB 4)-binding nociceptive sensory neurons. GFRA2 is required for the development of the myenteric nerve plexus and is an excellent candidate gene for Hirschsprung disease (HSCR). GFRalpha2 signaling is also needed for development of the parasympathetic islet innervation that is critical for vagally induced hormone secretion. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 46.2 kDa |
Note | 仅供科研使用 |