Recombinant Mouse Dr6/Tnfrsf21 Protein, His & Fc Tag
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产品编号
MOP2131
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别名
DR6, TR7, R74815, AA959878, tumor necrosis factor receptor superfamily, member 21
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规格
- 50ug
- 100ug
产品介绍
| Alias | DR6, TR7, R74815, AA959878, tumor necrosis factor receptor superfamily, member 21 |
| Catalog Number | MOP2131 |
| Molecular Name | Tnfrsf21 |
| Species | Mouse |
| Host | Mammalian cells |
| Size | 50ug, 100ug |
| Protein Family | Other protein |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
| Formulation | PBS |
| Background | Death receptor-6 (DR6), a member of the death domain-containing TNFR superfamily, is highly expressed in lymphoid tissues and regulated upon lymphocyte activation. Targeted disruption of DR6 results in enhanced CD4(+) T cell proliferation and T helper 2 differentiation in vitro. DR6 contains an extracellular region and an intracellular region, the intracellular region harbors a death domain that is critical for transduction of apoptotic signals. DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-κB and JNK. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 58.88 kDa |
| Note | 仅供科研使用 |
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