Recombinant Human DR1 Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human DR1 Protein, His Tag

Recombinant Human DR1 Protein, His Tag

产品编号

KMH999

别名

NC2, NC2B, NCB2, NC2 BETA, down regulator of transcription 1

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	NC2, NC2B, NCB2, NC2 BETA, down regulator of transcription 1
Catalog Number	KMH999
Molecular Name	DR1
Species	Human
Host	E. coli
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	Please contact our customer service for more information.
Formulation	PBS
Background	Dr1 is a general negative regulator of class II and class III gene expression. It binds to the basic repeat domain of TBP on promoter DNA and can prevent the RNA polymerase II holoenzyme, or its TFIIB and/or TFIIA subunits, from assembling into an initiation complex. Dr1 is phosphorylated in vivo and this modification affects its interaction with TBP. In addition, Dr1 interacts with the hyperphosphorylated form of Pol II and with the repression domain of the AREB6 repressor. Dr1 forms a heterodimer complex with DRAP1 through its histone fold domain.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	19.25 kDa
Note	仅供科研使用

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