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Recombinant Mouse DAN/Nbl1 Protein, His Tag

Recombinant Mouse DAN/Nbl1 Protein, His Tag

产品编号

MOP2126

别名

DAN, NO3, Dana, D4H1S1733E, NBL1, DAN family BMP antagonist

规格
  • 50ug
  • 100ug
产品介绍
AliasDAN, NO3, Dana, D4H1S1733E, NBL1, DAN family BMP antagonist
Catalog NumberMOP2126
Molecular NameNbl1
SpeciesMouse
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundDAN is a secreted glycoprotein related to Xenopus laevis cerberus. It is being referred to also as DAND1 [DAN domain family member 1]. The gene has been described also as NO3 gene, which shows tumor suppressor activity in cells transformed by the src oncogene. DAN belongs to a gene family, termed CAN family, that includes the head-inducing factor Gremlin, Cerberus, PRDC. DAN and several other members of the can family act as antagonists of BMP and appear to block BMP signaling by preventing bone morphogenetic proteins from interacting with their receptors. DAN has recently been demonstrated to have a tumor-suppressive activity in vitro and may have an important role in regulation of the entry of cells into the S phase.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight17.82 kDa
Note仅供科研使用

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