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Recombinant Mouse Ctnnb1 Protein, His Tag

Recombinant Mouse Ctnnb1 Protein, His Tag

产品编号

MOP2116

别名

Bfc, Mesc, Catnb, catenin(cadherin associated protein), beta 1

规格
  • 50ug
  • 100ug
产品介绍
AliasBfc, Mesc, Catnb, catenin(cadherin associated protein), beta 1
Catalog NumberMOP2116
Molecular NameCtnnb1
SpeciesMouse
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
Backgroundβ-catenins are cytoplasmic proteins that are ubiquitously expressed. These proteins associate with E-cadherin at cellular junctions. β-catenin interacts with TCF and LEF transcription factors and is an essential member of the Wingless-Wnt signal transduction pathway. The adenomatous polyposis coli (APC) tumor-suppressor protein, together with Axin and GSK3β, form a Wnt-regulated signaling complex that mediates phosphorylation-dependent degradation of β-catenin by the proteasome. APC and Siah-1 mediate a novel β-catenin degradation pathway linking p53 activation to cell cycle control. Activating mutations in the human β-catenin gene have been found in human colon cancer and melanomas.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight87.34 kDa
Note仅供科研使用

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