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Recombinant Mouse Clusterin/Clu Protein, His Tag

Recombinant Mouse Clusterin/Clu Protein, His Tag

产品编号

MOP2102

别名

Cli, ApoJ, Sgp2, SP 40, Sgp 2, Sugp 2, AI893575, D14Ucla3, Msgp 2, clusterin

规格
  • 50ug
  • 100ug
产品介绍
AliasCli, ApoJ, Sgp2, SP 40, Sgp 2, Sugp 2, AI893575, D14Ucla3, Msgp 2, clusterin
Catalog NumberMOP2102
Molecular NameClu
SpeciesMouse
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundClusterin mRNA and Clusterin protein are shown to increase with androgen treatment. Binding of clusterin to the LDL-Receptor plays a role in the pathogenesis of membranous glomerulonephritis. Clusterin is down regulated in CaP in association with matched benign controls. Clusterin is involved in cellular senescence and tumorigenesis. Clusterin is involved in photo-oxidative cell death pathway. Clusterin is a functional tumor marker for the diagnosis of pediatric large cell lymphoma. Clusterin is activated in low pH. Clusterin is involved in the inhibition of NF-kappaB signaling through stabilization of IkappaBs thus results in suppression of tumor cell motility. N-terminal deletion of clusterin is vital for its alterations of biogenesis in esophageal squamous cell carcinoma.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight46.97 kDa
Note仅供科研使用

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