Recombinant Mouse Clusterin/Clu Protein, His Tag
-
产品编号
MOP2102
-
别名
Cli, ApoJ, Sgp2, SP 40, Sgp 2, Sugp 2, AI893575, D14Ucla3, Msgp 2, clusterin
-
规格
- 50ug
- 100ug
Alias | Cli, ApoJ, Sgp2, SP 40, Sgp 2, Sugp 2, AI893575, D14Ucla3, Msgp 2, clusterin |
Catalog Number | MOP2102 |
Molecular Name | Clu |
Species | Mouse |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | Clusterin mRNA and Clusterin protein are shown to increase with androgen treatment. Binding of clusterin to the LDL-Receptor plays a role in the pathogenesis of membranous glomerulonephritis. Clusterin is down regulated in CaP in association with matched benign controls. Clusterin is involved in cellular senescence and tumorigenesis. Clusterin is involved in photo-oxidative cell death pathway. Clusterin is a functional tumor marker for the diagnosis of pediatric large cell lymphoma. Clusterin is activated in low pH. Clusterin is involved in the inhibition of NF-kappaB signaling through stabilization of IkappaBs thus results in suppression of tumor cell motility. N-terminal deletion of clusterin is vital for its alterations of biogenesis in esophageal squamous cell carcinoma. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 46.97 kDa |
Note | 仅供科研使用 |