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Recombinant Human CDKN2C Protein, His Tag

Recombinant Human CDKN2C Protein, His Tag

产品编号

KMH855

别名

p18, INK4C, p18 INK4C, cyclin dependent kinase inhibitor 2C

规格
  • 50ug
  • 100ug
产品介绍
Aliasp18, INK4C, p18 INK4C, cyclin dependent kinase inhibitor 2C
Catalog NumberKMH855
Molecular NameCDKN2C
SpeciesHuman
HostE. coli
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
EndotoxinPlease contact our customer service for more information.
FormulationPBS
Backgroundp18INK4C is a member of the INK4 family of proteins that regulate the G1 to S cell cycle transition by binding to and inhibiting the pRb kinase activity of cyclin-dependent kinases 4 and 6. Mutation of p18INK4C impairs B-cell terminal differentiation and confers increased susceptibility to tumor development. p18INK4C can function as a tumor suppressor gene in Hodgkins lymphoma and its inactivation may contribute to the cell cycle deregulation and defective terminal differentiation characteristic of the Reed-Sternberg cells.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight18.48 kDa
Note仅供科研使用

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