Recombinant Human CDKN2C Protein, His Tag
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产品编号
KMH855
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别名
p18, INK4C, p18 INK4C, cyclin dependent kinase inhibitor 2C
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规格
- 50ug
- 100ug
| Alias | p18, INK4C, p18 INK4C, cyclin dependent kinase inhibitor 2C |
| Catalog Number | KMH855 |
| Molecular Name | CDKN2C |
| Species | Human |
| Host | E. coli |
| Size | 50ug, 100ug |
| Protein Family | Other protein |
| Purity | ≥90% as determined by SDS-PAGE |
| Purification | Affinity Purification |
| Endotoxin | Please contact our customer service for more information. |
| Formulation | PBS |
| Background | p18INK4C is a member of the INK4 family of proteins that regulate the G1 to S cell cycle transition by binding to and inhibiting the pRb kinase activity of cyclin-dependent kinases 4 and 6. Mutation of p18INK4C impairs B-cell terminal differentiation and confers increased susceptibility to tumor development. p18INK4C can function as a tumor suppressor gene in Hodgkins lymphoma and its inactivation may contribute to the cell cycle deregulation and defective terminal differentiation characteristic of the Reed-Sternberg cells. |
| Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
| Shipping Condition | This product is shipped on ice packs or dry ice. |
| Molecular Weight | 18.48 kDa |
| Note | 仅供科研使用 |
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