Recombinant Human CDKN1B Protein, His Tag
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产品编号
KMH854
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别名
KIP1, MEN4, CDKN4, MEN1B, P27KIP1, cyclin dependent kinase inhibitor 1B
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规格
- 50ug
- 100ug
Alias | KIP1, MEN4, CDKN4, MEN1B, P27KIP1, cyclin dependent kinase inhibitor 1B |
Catalog Number | KMH854 |
Molecular Name | CDKN1B |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | Please contact our customer service for more information. |
Formulation | PBS |
Background | KIP1 (cyclin-dependent kinase inhibitor 1B) is a kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation. Many tumorigenic processes modulate cell-cycle progression by regulating the levels of the cyclin-dependent kinase inhibitor KIP1. KIP1 binds to and inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4. The phosphorylation- and ubiquitination-dependent proteolysis of KIP1 is implicated in control of the G1-S transition in the cell cycle. KIP1 is critical for retinoblastoma protein (Rb)-induced cellular proliferative senescence. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 21.78 kDa |
Note | 仅供科研使用 |