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Recombinant Human CDKN1B Protein, His Tag

Recombinant Human CDKN1B Protein, His Tag

产品编号

KMH854

别名

KIP1, MEN4, CDKN4, MEN1B, P27KIP1, cyclin dependent kinase inhibitor 1B

规格
  • 50ug
  • 100ug
产品介绍
AliasKIP1, MEN4, CDKN4, MEN1B, P27KIP1, cyclin dependent kinase inhibitor 1B
Catalog NumberKMH854
Molecular NameCDKN1B
SpeciesHuman
HostE. coli
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
EndotoxinPlease contact our customer service for more information.
FormulationPBS
BackgroundKIP1 (cyclin-dependent kinase inhibitor 1B) is a kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation. Many tumorigenic processes modulate cell-cycle progression by regulating the levels of the cyclin-dependent kinase inhibitor KIP1. KIP1 binds to and inhibits cyclinE-Cdk2 complex, cyclinA-CDK2 and cyclinD1-CDK4. The phosphorylation- and ubiquitination-dependent proteolysis of KIP1 is implicated in control of the G1-S transition in the cell cycle. KIP1 is critical for retinoblastoma protein (Rb)-induced cellular proliferative senescence.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight21.78 kDa
Note仅供科研使用

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