Recombinant Human BSSP-4/PRSS22 Protein, His Tag
-
产品编号
KMH758
-
别名
BSSP 4, SP001LA, hBSSP 4, serine protease 22
-
规格
- 50ug
- 100ug
Alias | BSSP 4, SP001LA, hBSSP 4, serine protease 22 |
Catalog Number | KMH758 |
Molecular Name | PRSS22 |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | BrainSpecific Serine Protease 4 (BSSP4) is a serine protease that preferentially cleaves the synthetic substrate HDLeuThrArgpNA compared to tosylGlyProArgpNA. BSSP4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after arginine and lysine residues. However, BSSP4 is less susceptible to inhibition by common trypsin inhibitors such as aprotinin, alpha1antitrypsin and secretory leukocyte protease inhibitor. BSSP4 efficiently converts prourokinase type plasminogen activator to its mature, active form. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 31.35 kDa |
Note | 仅供科研使用 |