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Recombinant Human BID/BH3-interacting domain death agonist protein Protein, No Tag

Recombinant Human BID/BH3-interacting domain death agonist protein Protein, No Tag

产品编号

KMH741

别名

FP497, BH3 interacting domain death agonist

规格
  • 50ug
  • 100ug
产品介绍
AliasFP497, BH3 interacting domain death agonist
Catalog NumberKMH741
Molecular NameBID
SpeciesHuman
HostE. coli
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
EndotoxinPlease contact our customer service for more information.
FormulationPBS
BackgroundBID is a BH3 interacting death domain that heterodimerizes with either agonist BAX or antagonist BCL2. BID is a member of the BCL-2 family of cell death regulators and is a mediator of mitochondrial damage induced by caspase-8 (CASP8). BID initiates apoptosis by binding to regulatory sites on prosurvival BCL2 proteins to directly neutralize their function. Multiple alternatively spliced transcript variants of BID have been found, but the full-length nature of some variants has not been defined. BID together with Cathepsins play an important role in the actions of Camptothecin on breast cancer cells.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight21.45 kDa
Note仅供科研使用

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