Recombinant Human BCL2L1/BCL-Xl Protein, His Tag
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产品编号
KMH729
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别名
BCLX, BCL2L, Bcl X, PPP1R52, BCL XL/S, BCL2 like 1
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规格
- 50ug
- 100ug
Alias | BCLX, BCL2L, Bcl X, PPP1R52, BCL XL/S, BCL2 like 1 |
Catalog Number | KMH729 |
Molecular Name | BCL2L1 |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | Please contact our customer service for more information. |
Formulation | PBS |
Background | The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 23.32 kDa |
Note | 仅供科研使用 |