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Recombinant Human BCL2L1/BCL-Xl Protein, His Tag

Recombinant Human BCL2L1/BCL-Xl Protein, His Tag

产品编号

KMH729

别名

BCLX, BCL2L, Bcl X, PPP1R52, BCL XL/S, BCL2 like 1

规格
  • 50ug
  • 100ug
产品介绍
AliasBCLX, BCL2L, Bcl X, PPP1R52, BCL XL/S, BCL2 like 1
Catalog NumberKMH729
Molecular NameBCL2L1
SpeciesHuman
HostE. coli
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
EndotoxinPlease contact our customer service for more information.
FormulationPBS
BackgroundThe protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight23.32 kDa
Note仅供科研使用

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