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Recombinant Mouse B7-2/Cd86 Protein, Fc Tag

Recombinant Mouse B7-2/Cd86 Protein, Fc Tag

产品编号

MOP2073

别名

B7, B70, MB7, B7 2, B7.2, CLS1, Ly58, ETC 1, Ly 58, MB7 2, Cd28l2, TS/A 2, CD86 antigen

规格
  • 50ug
  • 100ug
产品介绍
AliasB7, B70, MB7, B7 2, B7.2, CLS1, Ly58, ETC 1, Ly 58, MB7 2, Cd28l2, TS/A 2, CD86 antigen
Catalog NumberMOP2073
Molecular NameCd86
SpeciesMouse
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS
BackgroundB7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant costimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 2 - 1 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight49.2 kDa
Note仅供科研使用

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