Recombinant Mouse B7-2/Cd86 Protein, Fc Tag
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产品编号
MOP2073
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别名
B7, B70, MB7, B7 2, B7.2, CLS1, Ly58, ETC 1, Ly 58, MB7 2, Cd28l2, TS/A 2, CD86 antigen
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规格
- 50ug
- 100ug
Alias | B7, B70, MB7, B7 2, B7.2, CLS1, Ly58, ETC 1, Ly 58, MB7 2, Cd28l2, TS/A 2, CD86 antigen |
Catalog Number | MOP2073 |
Molecular Name | Cd86 |
Species | Mouse |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | PBS |
Background | B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant costimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 2 - 1 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 49.2 kDa |
Note | 仅供科研使用 |