Recombinant Human B2M Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human B2M Protein, His Tag

Recombinant Human B2M Protein, His Tag

产品编号

KMH712

别名

IMD43, CDABP0092, HDCMA22P, beta 2 microglobulin

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	IMD43, CDABP0092, HDCMA22P, beta 2 microglobulin
Catalog Number	KMH712
Molecular Name	B2M
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Other protein
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Beta-2-microglobulin (B2M), is a component of MHC class I molecules which belongs to the beta-2-microglobulin family. B2M is present on all nucleated cells (excludes red blood cells). B2M associates not only with the alpha chain of MHC class I molecules, but also with class I-like molecules such as CD1 and Qa. An additional function of B2M is association with the HFE protein, together regulating the expression of hepcidin in the liver which targets the iron transporter ferroportin on the cytoplasmic membrane of enterocytes and macrophages for degradation resulting in decreased iron uptake from food and iron release from recycled red blood cells respectively. Loss of this function causes iron excess and hemochromatosis. Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP).
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	10.89 kDa
Note	仅供科研使用

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