Recombinant Human APE/APEX1 Protein, No Tag
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产品编号
KMH678
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别名
APE, APX, APE1, APEN, APEX, HAP1, REF1, apurinic/apyrimidinic endodeoxyribonuclease 1
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规格
- 50ug
- 100ug
Alias | APE, APX, APE1, APEN, APEX, HAP1, REF1, apurinic/apyrimidinic endodeoxyribonuclease 1 |
Catalog Number | KMH678 |
Molecular Name | APEX1 |
Species | Human |
Host | E. coli |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | Please contact our customer service for more information. |
Formulation | PBS |
Background | Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5 to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene, all encode the same protein. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 34.87 kDa |
Note | 仅供科研使用 |