Recombinant Human HGF/HPTA Protein, His Tag
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产品编号
KMH612
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别名
SF, HGFB, HPTA, F TCF, DFNB39, hepatocyte growth factor
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规格
- 50ug
- 100ug
Alias | SF, HGFB, HPTA, F TCF, DFNB39, hepatocyte growth factor |
Catalog Number | KMH612 |
Molecular Name | HGF |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | Please contact our customer service for more information. |
Formulation | PBS |
Background | It is a potent mitogen for mature parenchymal hepatocytes and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Human HGF is expressed as a linear 697 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (α-chain and beta-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The α-chain consists of 463 amino acid residues and four kringle domains. The beta-chain consists of 234 amino acid residues. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 83.46 kDa |
Note | 仅供科研使用 |