Recombinant Human HMGB1 Protein, His Tag
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产品编号
KMH574
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别名
HMG1, HMG3, HMG 1, SBP 1, high mobility group box 1
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规格
- 50ug
- 100ug
Alias | HMG1, HMG3, HMG 1, SBP 1, high mobility group box 1 |
Catalog Number | KMH574 |
Molecular Name | HMGB1 |
Species | Human |
Host | Mammalian cells |
Size | 50ug, 100ug |
Protein Family | Other protein |
Purity | ≥90% as determined by SDS-PAGE |
Purification | Affinity Purification |
Endotoxin | < 1.0 EU per ug of the protein as determined by the LAL method. |
Formulation | Supplied as solution form in 50mM Tris HCl pH 7, 150mM NaCl, 1mM EDTA./Lyophilized from 50mM Tris HCl pH 7, 150mM NaCl, 1mM EDTA. |
Background | High-mobility group box 1 protein (HMGB1), previously known as HMG-1 or amphoterin, is a member of the high mobility group box family of non-histone chromosomal proteins. Human HMGB1 is expressed as a 3 kDa, 215 amino acid (aa) single chain polypeptide containing three domains: two N-terminal globular, 7 aa positively charged DNA-binding domains (HMG boxes A and B), and a negatively charged 3 aa C-terminal region that contains only Asp and Glu.4, 5 Residues 27 - 43 and 178 - 184 contain a NLS. Posttranslational modifications of the molecule have been reported, with acetylation occurring on as many as 17 lysine residues. |
Storage Condition | Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles. |
Shipping Condition | This product is shipped on ice packs or dry ice. |
Molecular Weight | 26.97 kDa |
Note | 仅供科研使用 |