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Recombinant Human B-Gal/GLB1 Protein, His Tag

Recombinant Human B-Gal/GLB1 Protein, His Tag

产品编号

KMH541

别名

EBP, ELNR1, MPS4B, galactosidase beta 1

规格
  • 50ug
  • 100ug
产品介绍
AliasEBP, ELNR1, MPS4B, galactosidase beta 1
Catalog NumberKMH541
Molecular NameGLB1
SpeciesHuman
HostMammalian cells
Size50ug, 100ug
Protein FamilyOther protein
Purity≥90% as determined by SDS-PAGE
PurificationAffinity Purification
Endotoxin< 1.0 EU per ug of the protein as determined by the LAL method.
FormulationPBS, pH7.5
BackgroundGalactosidase is a lysosomal Galactosidase that hydrolyzes the terminal Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature Galactosidase protein associates with Cathepsin A and Neuraminidase 1 to form the lysosomal multienzyme complex. An alternative splicing at the RNA level of Galactosidase results a catalytically inactive Galactosidase that plays an important role in vascular development. Defects of galactosidase (GLB1) are the cause of diseases like GM1-gangliosidosis which is a lysosomal storage disease and Morquio Syndrome B that cause patients to have abnormal elastic fibers. More than 1 mutations have been identified for Galactosidase, which result in different residual activities of the mutant enzymes and a spectrum of symptoms in the two related diseases.
Storage ConditionStore the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping ConditionThis product is shipped on ice packs or dry ice.
Molecular Weight74.66 kDa
Note仅供科研使用

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