Recombinant Human FOLR1 Protein, His Tag_天津卡梅德科技发展有限公司

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Recombinant Human FOLR1 Protein, His Tag

Recombinant Human FOLR1 Protein, His Tag

产品编号

KMH528

别名

FBP, FOLR, FRalpha, folate receptor alpha

规格

50ug
100ug

DATASHEET MSDS

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产品介绍

Alias	FBP, FOLR, FRalpha, folate receptor alpha
Catalog Number	KMH528
Molecular Name	FOLR1
Species	Human
Host	Mammalian cells
Size	50ug, 100ug
Protein Family	Biomarker
Purity	≥90% as determined by SDS-PAGE
Purification	Affinity Purification
Endotoxin	< 1.0 EU per ug of the protein as determined by the LAL method.
Formulation	PBS
Background	Folate Receptor 1 (FOLR1) is also known as Folate receptor alpha, Folate Binding Protein (FBP), FOLR, and is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Mature FOLR1 is an N-glycosylated protein that is anchored to the cell surface by a GPI linkage. FOLR1 is predominantly expressed on epithelial cells and is dramatically upregulated on many carcinomas. FOLR1 is internalized to the endosomal system where it dissociates from its ligand before recycling to the cell surface. A soluble form of FOLR1 can be proteolytically shed from the cell surface into the serum and breast milk. Defects in FOLR1 are the cause of neurodegeneration due to cerebral folate transport deficiency (NCFTD). NCFTD is an autosomal recessive disorder resulting from brain-specific folate deficiency early in life.
Storage Condition	Store the product under sterile conditions after opening at -20℃ to -80℃ for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition	This product is shipped on ice packs or dry ice.
Molecular Weight	25.74 kDa
Note	仅供科研使用

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